Casa di Cura Santa Chiara
Via Maggiore Guida, 9 | Partinico (PA)
​Studio dott. Matteo Tutino
​Via Sammartino, 55 | Palermo (PA)
Tel: +39 331 221 5288
VITAMINA C LEVOGIRA
DERMATOLOGICAL CASES & STUDYES
Vitamina C Levogira 15%, Melatonina e Resveratrolo nella regolazione dell’omeostasi cutanea: Applicazioni cliniche e nuove prospettive.
Levogira Vitamin C 15%, Melatonin and Resveratrol in the regulation of skin homeostasis:
Clinical application and new perspectives
M. Tutino
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SUMMARY
Lo studio si prefigge di fare chiarezza sull’importanza della vitamina C levogira stabilizzata al 15% con procedimento brevettato e le sue applicazioni in dermatologia e medicina estetica, unitamente alla melatonina e resveratrolo.
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The study aims to shed light on the importance of levogira vitamin C stabilized at 15% with patented process and its applications in dermatology and aestethic medicine together with melatonin and resveratrol.
IPERPIGMENTAZIONE
JOURNAL OF PLASTIC DERMATOLOGY (PG.17)
Until now it has been difficult to use l-ascorbic acid in cosmetic preparations because of its instability. In this study we used the antioxidant action of melatonin and resver- atrol to stabilize L-ascorbic acid.
The results of stability tests show that when the three substances are mixed together there is an increase of the L-ascorbic acid stability. The clinical application of the cosmetic serum containing L-ascorbic acid, melatonin and resveratrol promotes re-epithelialization and adjust the color of the hyperpig- mented skin.
KEY WORDS: L-ascorbic acid, melatonin, resveratrol, stability.
AUTHORS: Dott. Matteo Tutino
PSORIASI E TNA-ALFA
JOURNAL OF PLASTIC SURGERY AND DERMATOLOGY
The molecular complex consisting of Vitamin C and melatonin is effective in regulating cellular processes by regulating the expression of various cytokines as Et1 (Endothelin 1), PGE (prostaglandin E), TNFα (tumor necrosis factor alpha) and the proopiomelanocortin (POMC).
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Starting from these premises, our study has highlighted how melatonin, resveratrol and Vitamin C, if combined, are able to perform their function at the cellular and biomolecular level by intervening in the processes of melanogenesis and tissue repair, thanks to greater stability as demonstrated from our studies at 55 and 125 days, so to guarantee the availability of these substances during topical treatment, unlike most cosmetics and medical products that use these substances individually.
In fact, it has been seen how the treatment of skin hyperpigmentation, psoriasis in different regions of the body and scarring processes, particularly in diabetics, respond in the vast majority of cases with excellent results by restoring normal tissue integrity and a normal and homogeneous skin pigmentation.